Aldol Condensation-Type Group Transfer Copolymerizations of Silyl (Di)Enolates

Chemoselective silyl transfer in the Mukaiyama aldol reaction promoted by super silyl Lewis acid.

In the silyl Lewis acid-promoted Mukaiyama aldol reaction, the steric and electronic properties of the silyl group on the silyl Lewis acid influence the reaction mechanism and product distribution. When super silyl triflates such as (TMS)3SiOTf and (TES)3SiOTf are used as Lewis acids, the silyl group of the silyl enol ether chemoselectively transfers to the product. The mechanistic details have...

Aldol type Condensation Reactions of Acyl Ketene Dithioacetals

Organic Synthesis: Aldol Condensation Reaction

In an "aldol addition" reaction an enol or enolate of an aldehyde or ketone reacts with a second aldehyde or ketone forming a new carbon-carbon bond which makes the aldol reaction an important reaction for organic synthesis. Originally, the aldol reaction used ethanal (see below) and therefore the product contained both an aldehyde and an alcohol functional group; thus it became known as the al...

Organic Synthesis: Aldol Condensation Reaction

In an "aldol addition" reaction an enol or enolate of an aldehyde or ketone reacts with a second aldehyde or ketone forming a new carbon-carbon bond. This makes the aldol reaction an important reaction for organic synthesis. Originally, the aldol reaction used ethanal (see below) and therefore the product contained both an aldehyde and an alcohol functional group; thus it became known as the al...

The Aldol Condensation Preparation of 4-Methoxybenzalacetone